(KO Validated) DNMT3A Polyclonal Antibody - E-AB-67769

(KO Validated) DNMT3A Polyclonal Antibody Sizes: 60μL, 120μL, 200μL Catalogue Numbers: E-AB-67769-60, E-AB-67769-120, E-AB-67769-200 Citations, Manuals and MSDS Available upon request. Abbreviation: DNMT3A Target Synonym: DNMT3A; DNMT3A2; M.HsaIIIA; TBRS; DNMT3A Research Areas: Cancer,Epigenetics and Nuclear Signaling Conjugation: Unconjugated Host: Rabbit Species Reactivity: Human, Rat Application: WB Isotype: IgG Clonality: Polyclonal UNIProt ID: Q9Y6K1 Background: CpG methylation is an epigenetic modification that is important for embryonic development, imprinting, and X-chromosome inactivation. Studies in mice have demonstrated that DNA methylation is required for mammalian development. This gene encodes a DNA methyltransferase that is thought to function in de novo methylation, rather than maintenance methylation. The protein localizes to the cytoplasm and nucleus and its expression is developmentally regulated. Concentration: 1 mg/mL Immunogen: Recombinant fusion protein of human DNMT3A Buffer: PBS with 0.05% proclin300, 50% glycerol, pH7.3. Purification Method: Affinity purification Dilution: WB 1:500-1:2000 Calculated MW: 16kDa/81kDa/101kDa Observed MW: 140kDa Storage: -20°C/One year. Avoid freeze / thaw cycles. Shipping: Ice bag Research Use Only