AZD-8055

Catalog#: C-1065 Targets: mTOR Synonym: AZD8055; AZD-8055; AZD 8055 Technical Data Product Name: AZD-8055 Chemical Formula: C25H31N5O4 Molecular Weight: 465.54 CAS#: 1009298-09-2 Appearance: Solid powder Purity: > 99% by HPLC  Solubility: Soluble in DMSO Storage: Room temperature for months, or -20ºC for three years DescriptionAZD-8055 is an inhibitor of the mammalian target of rapamycin (mTOR) with potential antineoplastic activity. mTOR kinase inhibitor AZD-8055 inhibits the serine/threonine kinase activity of mTOR, resulting in decreased expression of mRNAs necessary for cell cycle progression, which may induce cell cycle arrest and tumor cell apoptosis. mTOR phosphorylates transcription factors, such as S6K1 and 4E-BP1, which stimulate protein synthesis and regulate cell growth, proliferation, motility, and survival.