Activin A, Active

Product DescriptionCurrent Lead Time7-14 DaysProduct Specifications Species Human Expression System E. coli Purity 95% by SDS-PAGE Activity Biological activity is assessed by the ability to induce cytotoxicity of MPC-11 cells and was found to be 8.8ng/ml corresponding to a specific activity of 1.1 x 105 units/mg. Activity Assay Animal Component Free (ACF) Yes Molecular Weight Structure Contact for Details Endotoxin Concentration Not Available Purification Method Not Available Form Lyophilized freeze dried powder. Formulation Human Activin-A was lyophilized from a concentrated 1mg/ml protein solution containing 0.1% TFA. *For Research Use OnlyNotesActivins are homodimers or heterodimers of the different β subunit isoforms, part of the TGFβ family. Mature Activin A has two 116 amino acids residues βA subunits (βA-βA). Activin displays an extensive variety of biological activities, including mesoderm induction, neural cell differentiation, bone remodelling, haematopoiesis, and reproductive physiology. Activins takes part in the production and regulation of hormones such as FSH, LH, GnRH and ACTH. Cells that are identified to express Activin A include fibroblasts, endothelial cells, hepatocytes, vascular smooth muscle cells, macrophages, keratinocytes, osteoclasts, bone marrow monocytes, prostatic epithelium, neurons, chondrocytes, osteoblasts, Leydig cells, Sertoli cells, and ovarian granulosa cells.