*Human Pai 1 Recombinant Lrp Binding Negative

Select this product for Molecular Innovations name, PAI-1 mutant - stable, no LRP binding and product number, HPAI-R76E-I91L.Human PAI-1 Recombinant LRP Binding Negative from Innovative Research has been recombinantly produced in E. coli and purified by affinity chromatography. This is a Frozen liquid buffered in 0.05M Sodium Phosphate; 0.1M NaCl; 1mM EDTA; pH 6.6 and a purity of >95% as determined by SDS-PAGE. More Details: Species: Human Target: PAI-1 Purification Method: Affinity purified Purity: >95% as determined by SDS-PAGE Analysis Source: E. coli Storage Conditions: -20 C Additional Information: PAI-1 mutant with subsitution of Glutamic Acid for Arginine at postion 76. This greatly reduces PAI-1 binding to low density lipoprotein receptor-related protein (LRP). An additional mutation (Isoleucine 91 to Leucine) provides increased stability for long-term binding experiments. This product can be used as a control in applications like ELISA and Western Blot. It can be used in a wide range of in vitro applications, including blocking/inhibition, fibrinolysis, plasminogen activation, receptor binding, in hypertension studies, for protein-protein interactions, and more. At Innovative Research, we provide reliable, consistent products that deliver reliable, consistent results.