CD223 (LAG-3) Monoclonal Antibody (eBioC9B7W (C9B7W)), Super Bright™ 600, eBioscience™

PRODUCT DETAILSHost: RatIsotype: IgG1, kappaClonality: MonoclonalClone: eBioC9B7W (C9B7W)Format: Super Bright™ 600Reactivity: MouseApplication: Flow CytometryTested Dilution: 1.0 µg/testConcentration: 0.2 mg/mLStorage: 4° C, store in dark, DO NOT FREEZE!Formulation: PBS, pH 7.2, containing 0.09% sodium azidePurification: Affinity chromatographyData Sheet: TDS Specific InformationDescription: The eBioC9B7W monoclonal antibody recognizes mouse CD223 (LAG-3, LAG3) protein expressed by activated alpha/beta-TCR bearing T cells, a subset of gamma/delta-TCR bearing T cells and a subset of NK cells. CD223 is a 70 kDa type I transmembrane protein with a structure that is similar to CD4. However, a soluble form of human CD223 has been detected by ELISA in human serum, and data suggest that mouse CD223 is proteolytically cleaved in the D4 domain. This results in a 54 kDa fragment containing all the extracellular domains, and a 16 kDa fragment containing the intracellular and transmembrane domains