APC-Cyanine7 Anti-Mouse CD45.1 (A20)

TDS | SDS The A20 antibody reacts with mouse CD45.1, also known as Ly5.1, which is a strain-specific allelic form of the CD45 Leukocyte Common Antigen (LCA). Functionally, CD45 is a protein tyrosine phosphatase whose broad cell distribution supports a critical role in many leukocyte functions, including regulation of signal transduction and cell activation associated with the T cell and B cell receptors. The A20 antibody is typically used as a leukocyte marker in Ly5.1 mouse strains: SJL/J, DA, STS/A and RIII. The antibody has been demonstrated to specific for CD45.1 and is not cross-reactive with CD45.2 bearing cells.   Recent Publications: Fu Z, Dean JW, Xiong L, et al. Mitochondrial transcription factor A in RORγt+ lymphocytes regulate small intestine homeostasis and metabolism. Nat Commun. 2021 Jul 22;12(1):4462. doi: 10.1038/s41467-021-24755-9. PMID: 34294718. » View on Nature Communications Baba T, Yoshida T, Tanabe Y, et al. Cytoplasmic DNA accumulation preferentially trigger