APC Anti-Mouse Foxp3 (MF23)

TDS | SDS The MF23 antibody reacts with mouse Foxp3, a 50-55 kDa transcription factor which is a central regulator of T cell activity and is critical for the development and function of regulatory T cells (Tregs). Foxp3 is a member of the forkhead box or winged helix family of transcription factors and is expressed at constitutively high levels in Treg cells. Forced expression of Foxp3 in conventional T cells results in the upregulation of Treg associated molecules such as CD25, CTLA-4, and GITR and is sufficient to impart suppressive functional activity to these cells. Name APC Anti-Mouse Foxp3 (MF23) Cat. No. 20-0191 Alternative Names Forkhead box P3, Scurfin, JM2 Gene ID 20371 Clone MF23 Isotype Rat IgG2b Reactivity Mouse Format APC Application Flow Cytometry decorateTable('product-attribute-specs-table')