APC Anti-Mouse CD45.2 (104)

TDS | SDS The 104 antibody reacts with mouse CD45.2, also known as Ly5.2, which is a strain-specific allelic form of the CD45 Leukocyte Common Antigen (LCA). Functionally, CD45 is a protein tyrosine phosphatase whose broad cell distribution supports a critical role in many leukocyte functions, including regulation of signal transduction and cell activation associated with the T cell and B cell receptors. The 104 antibody is typically used as a leukocyte marker in Ly5.2 mouse strains C57BL/6, BALB/c, C58, DBA/1, DBA/2, C3H/He, CBA, 129, A and AKR. The antibody has been demonstrated to be specific for CD45.2 and is not cross-reactive with CD45.1-bearing cells.   Recent Publications: Rahim T, Levinson MA, Carufe KEW, Burak M, Meas R, Maher S, Bothwell ALM, Gades N, Sweasy JB. The hematopoietic compartment is sufficient for lupus development resulting from the POLB-Y265C mutation. PLoS One. 2022 Apr 29;17(4):e0267913. doi: 10.1371/journal.pone.0267913. PMID: 35486639; PMCID: PMC9053796.