SLU-PP-332

SLU-PP-332 (REV-ERB Agonist) Primary Function: Circadian rhythm enhancement, fat metabolism, muscle preservation Research Use: Metabolic disorders, obesity, sarcopenia, mitochondrial function Molecular Formula: C21H17ClFNO3 CAS Number: N/A (research compound) Synonyms: SLUPP332, REV-ERBα/β agonist, Circadian regulator compound Description: SLU-PP-332 is a potent REV-ERBα and REV-ERBβ nuclear receptor agonist developed to modulate circadian gene expression, lipid metabolism, and muscle physiology. By activating REV-ERBs, SLU-PP-332 regulates core metabolic pathways, including fat oxidation, glucose homeostasis, and muscle protein preservation—without the need for calorie restriction or increased physical activity. It is currently used in advanced research into obesity, sarcopenia, and circadian disruption. Mechanism of Action: Activates REV-ERBα/β nuclear receptors Suppresses BMAL1, modulating circadian genes and metabolic pathways Enhances mitochondrial oxidative capacity Promotes l