PE 22-28

PE 22-28 Primary Function: Neuroprotection, cognitive enhancement, anti-apoptotic support Research Use: Neurodegenerative disease models, memory function, brain repair Molecular Formula: C33H56N10O6 CAS Number: 127425-94-3 Synonyms: Peptide E fragment 22-28, Pro-Gly-Pro-Ile-Gly-Ser-Arg Description: PE 22-28 is a synthetic fragment of Peptide E, a naturally occurring opioid peptide derived from proenkephalin A. This heptapeptide is studied for its potent neuroprotective and anti-apoptotic effects, especially in models of ischemic brain injury and neurodegenerative diseases. Research shows that PE 22-28 may promote neuronal survival, enhance synaptic plasticity, and modulate neuroinflammation, making it a unique candidate for studies related to stroke recovery, memory support, and neural regeneration. Mechanism of Action: Inhibits neuronal apoptosis via mitochondrial protection Modulates microglial activation and cytokine signaling Enhances neurogenesis and synaptic repair pathways Cr