
MOTS-C
MOTS-c (Mitochondrial Open-Reading Frame of the 12S rRNA Type-c) Primary Function: Metabolic regulation, mitochondrial optimization, cellular stress resistance Research Use: Obesity, insulin sensitivity, endurance, longevity, mitochondrial function Molecular Formula: C38H62N10O15 CAS Number: 1625585-96-4 Synonyms: Mitochondrial-derived peptide MOTSc, MOTS-c peptide Description: MOTS-c is a mitochondria-encoded peptide composed of 16 amino acids that plays a pivotal role in metabolic homeostasis. Unlike most peptides, which are encoded in the nuclear genome, MOTS-c is transcribed from the mitochondrial 12S rRNA gene and has been shown to regulate glucose metabolism, fat utilization, and insulin sensitivity. It has demonstrated promising results in aging, obesity, and exercise endurance models, making it a strong candidate for mitochondrial-related disease research. Mechanism of Action: Activates AMPK signaling, promoting cellular energy balance and fat oxidation Increases glucose upt