CMS-121
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CMS-121

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CMS-121 Primary Function: Mitochondrial protection, cognitive enhancement, anti-aging support Research Use: Neurodegeneration, metabolic health, Alzheimer’s disease, lifespan extension Molecular Formula: C17H16F3NO3 CAS Number: 1353224-53-9 Synonyms: CMS 121, Fisetin derivative, Salk CMS-121 Description: CMS-121 is a fisetin-derived neuroprotective compound developed for its potent effects on cognitive preservation, mitochondrial health, and metabolic regulation. Engineered to improve bioavailability and blood-brain barrier permeability over fisetin, CMS-121 has demonstrated robust anti-aging and neuroprotective benefits in preclinical studies. It is currently under investigation as a geroprotective agent in research on Alzheimer’s disease, cognitive decline, and oxidative stress reduction. Mechanism of Action: Activates AMPK and PGC-1α, enhancing mitochondrial biogenesis Reduces lipid peroxidation and oxidative stress Protects neurons against toxic protein accumulation Improves syn

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