BAM-15

BAM-15 Primary Function: Mitochondrial uncoupler, fat oxidation, metabolic enhancement Research Use: Obesity, fatty liver disease, mitochondrial research, longevity studies Molecular Formula: C17H14ClFN3OS CAS Number: 2030077-06-1 Synonyms: BAM15, Mitochondrial protonophore BAM-15 Description: BAM-15 is a novel mitochondrial uncoupler known for its ability to increase energy expenditure without raising core body temperature—a major limitation of previous uncouplers like DNP. BAM-15 works by dissipating the proton gradient across the mitochondrial membrane, thereby enhancing fat oxidation, reducing reactive oxygen species (ROS), and improving insulin sensitivity in preclinical models. It is currently under investigation for applications in obesity, non-alcoholic fatty liver disease (NAFLD), and lifespan extension. Mechanism of Action: Uncouples oxidative phosphorylation in mitochondria Increases fatty acid oxidation and metabolic rate Decreases mitochondrial ROS production Improves i