RalA Protein, Human, Recombinant, Biotinylated

Ras-related protein Ral-A (RALA) is a member of the Ras GTPase family and shares a high structural similarity with RAS proteins (1). In human cells, the two protein isoforms, RALA and RALB, have been shown to play roles in the proliferation, survival, and metastasis of a variety of human cancers. RALA and RALB share 81% sequence homology with one another and more than 50% sequence homology with RAS. Given their importance in cancer biology, RAL proteins have emerged as desirable clinical targets (2). Recombinant RalA protein with the N-terminal AviTag™ peptide and His-tag is produced in E. coli cells and site-specifically biotinylated at AviTag with BirA enzyme. Tag(s): The N-terminal 8XHis and AviTagAmino Acids: 1-206 of RalA (UniProt # P11233) Catalog # RALA-B-301 Storage buffer: 20 mM Tris-HCl, pH 7.5, 100 mM NaCl, 2 mM DTT, 10% Glycerol. Molecular weight: ~27 kDaPurity: >90% by Coomassie staining Storage is recommended at -80°C.  International Shipping:  Product requires shippin